Shaoxing Kaibang New Material Technology Co., Ltd

2,4,5-Trifluorobenzoic Acid C₇H₃F₃O₂ CAS NO.446-17-3

2,4,5-Trifluorobenzoic Acid: A Versatile Building Block for Organic Synthesis

 

 

2,4,5-Trifluorobenzoic Acid (TFBA) is an important aromatic compound widely used as a building block in organic synthesis. This colorless crystal compound, also known as 2,4,5-trifluorobenzenecarboxylic acid, has a molecular formula of C₇H₃F₃O₂ and a molecular weight of 192.09 g/mol.

The trifluoromethyl group (-CF3) in TFBA imparts unique properties to the compound, including high lipophilicity, low basicity, and strong electron-withdrawing ability. These features make it a versatile reagent for a wide range of organic reactions, including Grignard reactions, Suzuki coupling, peptide synthesis, and esterification.

 

 

 

 

[Density]: 1.5±0.1 g/cm³

[Boiling point]: 241.9±35.0 ℃ at 760 mmHg

[Melting point]: 94-96 ℃ (lit.)

[Molecular formula]: C7H₃F₃O₂

[Molecular weight]: 176.093

[Flash point]: 100.1±25.9 ℃

[Exact Mass]: 176.008514

[PSA]: 37.30000

[LogP]: 2.32

[Appearance]: White to light yellow crystal powder

[Vapor pressure]: 0.0±0.5 mmHg at 25℃

[Refractive Index]: 1.491

 

[ Storage conditions ]:

Store in a tightly sealed container in a cool, dry place. Packed in cardboard drums lined with plastic bags and outside, 25kg/drum.

[Stability]:

Use and store according to specifications, will not decompose, avoid contact with oxides

 

[ Molecular Structure ]:

1. Molar refractive index: 33.16

2. Molar volume (cm³/mol): 114.5

3. Isotonic specific volume (90.2K): 290.7

4. Surface tension (dyne/cm): 41.4

5. Polarizability (10⁻²⁴cm³): 13.14

Packing, Storage, Handling and Transportation

2,4,5-Trifluorobenzoic acid should be sealed in dry place at room temperature.

 

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